ISO/TS 21633:2021, “Label-free impedance technology to assess the toxicity of nanomaterials in vitro”. This document describes a methodology of a label free and real-time detection for non-invasive monitoring of cell-based assays to assess toxicity of nanomaterials to eukaryotic and prokaryotic cells. (link)
Published 11.08.2021
ISO/TS 23034:2021, “Nanotechnologies — Method to estimate cellular uptake of carbon nanomaterials using optical absorption”. This document describes a near-infrared optical absorption method to estimate the in vitro cellular uptake of carbon nanomaterials including both internalized and/or tightly adhered to the cell membrane from liquid dispersions. This is a simple method to screen carbon nanomaterials uptake; additional analysis using a different technique can be required if quantification is desired. (link)
Published 11.08.2021
ISO/TR 22293:2021 “Evaluation of methods for assessing the release of nanomaterials from commercial, nanomaterial-containing polymer composites”. This document aims to contribute to the understanding nanomaterial release by providing a guide to the information to be taken into account in determining the methods for identifying and evaluating releases of MNMs from matrices; providing a framework for understanding how these methods and the information they produce can support decision-making; and identifying opportunities for developing standards in this area. (link)