ECHA is carrying out a new targeted consultation of the proposal for the harmonised classification and labelling (CLH) of silver (EC 231-131-3; CAS 7440-22-4), submitted by Sweden and already the object of a first consultation in 2020.

A subsequent, targeted consultation was held in 2021, focusing on the preliminary summary of an in vivo comparative toxicokinetic study provided by the European Precious Metals Federation (EPMF) on silver acetate (AgAc), silver nitrate (AgNO3), one Agsilver nanoparticles (AgNP), and a sub-micron size powder-form (AgMP) of bulk elemental silver. The current consultation covers the final comparative toxicokinetic study as well as a 90-day study, EOGRTS and preliminary study on silver acetate; it also covers additional literature studies, included in the assessment of developmental neurotoxicity and neurotoxicity by the RAC in the course of the CLH process.

The consultation closes on May 17 and input can be provided at this link.