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ISO publishes two Nano Toxicology Standards

The International Organization for Standardization’s (ISO) Technical Committee on Nanotechnologies (TC 229) has recently published two new standards: ISO/TR 16197:2014 – Nanotechnologies – Compilation and description of toxicological screening methods for manufactured nanomaterials; and ISO/TS 16550:2014 – Nanotechnologies – Determination of silver nanoparticles potency by release of muramic acid from Staphylococcus aureus.

ISO/TR 16197 is a Technical Report that ‘provides a compilation and description of in vitro and in vivo methods that can be useful for the toxicological, including ecotoxicological, screening of engineered and manufactured nanomaterials’. Rather than replace or compete with existing regulatory requirements, it ‘is intended to complement other international efforts that address nanomaterial toxicology by focusing on screening methods used for preliminary assessment’. ISO/TS 27687:2008 and ISO/TS 80004-1 are said to be ‘indispensable’ for application of this new standard.

ISO/TS 16550 is a Technical Specification that ‘provides a test method for evaluating potency of silver nanoparticles to cell wall degradation of Staphylococcus aureus’. This standard was seen as necessary as ‘the antimicrobial properties of silver nanoparticles are being increasingly utilized in consumer products’ and ‘industries are producing wide varieties of AgNPs […] with little concern to their side effects’.


Follow this link to learn more and purchase ISO/TR 16197 and ISO/TS 16550.

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